[Solved] In experimental tests of enzyme evolution, where a gene encoding an enzyme is subjected to multiple cycles of random mutagenesis and selection for altered substrate specificity, the resulting enzyme had multiple amino acid changes associated with altered substrate specificity. Where in the enzyme were these amino acid changes located? A) only in the active site B) only in the active site or near the active site C) in or near the active site and at surface sites away from the active site D) only at surface sites away from the active site E) only in the hydrophobic interior of the folded protein Sexual Expression: Ways in which individuals express their sexuality, which can include thoughts, feelings, behaviors, and physical intimacy. Femme Porn: Pornography that is specifically designed to cater to the tastes, preferences, and sexual fantasies of women and femme-identified individuals. Brothels: Establishments specifically dedicated to providing premises for sexual activities between prostitutes and clients. Massage Parlors: Establishments where massage services are provided, sometimes implicated in discussions around the sex industry due to instances of illicit activities.