Use This Description to Answer the Following Question

question 50

Multiple Choice

Use this description to answer the following question.
A major group of G-protein-coupled receptors contains seven transmembrane α helices. The amino end of the protein lies at the exterior of the plasma membrane. Loops of amino acids connect the helices either at the exterior face or on the cytosol face of the membrane. The loop on the cytosol side between helices 5 and 6 is usually substantially longer than the others.
-If an animal cell suddenly lost the ability to produce GTP, what might happen to its signaling system?

• A) It would not be able to activate and inactivate the G protein on the cytoplasmic side of the plasma membrane.
• B) It could activate only the epinephrine system.
• C) It would be able to carry out reception and transduction but would not be able to respond to a signal.
• D) It would use ATP instead of GTP to activate and inactivate the G protein on the cytoplasmic side of the plasma membrane.
• E) It would employ a transduction pathway directly from an external messenger.

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