Garrod's Information About the Enzyme Alteration Resulting in Alkaptonuria Led

question 78

Multiple Choice

Garrod's information about the enzyme alteration resulting in alkaptonuria led to further understanding of these types of metabolic pathways in humans. Phenylketonuria (PKU) occurs when another enzyme in the pathway is altered or missing, resulting in a failure of phenylalanine (phe) to be metabolized to another amino acid: tyrosine. Tyrosine is an earlier substrate in the pathway altered in alkaptonuria. How might PKU affect the presence or absence of alkaptonuria?

• A) It would have no effect because PKU occurs several steps away in the pathway.
• B) It would have no effect because tyrosine is also available from the diet.
• C) Anyone with PKU must also have alkaptonuria.
• D) Anyone with PKU is born with a predisposition to later alkaptonuria.
• E) Anyone with PKU has mild symptoms of alkaptonuria.

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Definitions:

Nuts

Edible seeds enclosed in a hard shell, often characterized by their high fat and protein content.

Berries

Small, pulpy, and often edible fruits, typically juicy, rounded, brightly colored, and seed-containing.

Utility Function

A formula or mapping that indicates the level of happiness or preference an individual assigns to various bundles of goods or services, used in decision-making analysis.

Cocoa

A powder made from roasted and ground cacao seeds, used in the making of chocolate, as well as in baking and cooking.