Suppose That an Error in Transcription Alters the Formation of a Single

question 19

Multiple Choice

Suppose that an error in transcription alters the formation of a single tRNA molecule in a cell.The altered tRNA still attaches to the same amino acid (Phe) ,but its anticodon loop has the sequence AAU,which binds to the mRNA codon UUA (usually specifying the amino acid leucine,Leu) .What will be the effect on the translation of polypeptides in this cell?

• A)The altered tRNA will cause this mRNA to make only nonfunctioning product.
• B)The tRNA-Leu will not be able to enter the ribosome to bind to the UUA codon.
• C)One altered tRNA molecule will have little effect because it will compete with many "normal" ones.
• D)The altered tRNA will result in an amino acid variant in all copies of the protein.

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