The Most Commonly Occurring Mutation in People with Cystic Fibrosis

question 4

Multiple Choice

The most commonly occurring mutation in people with cystic fibrosis is a deletion of a single codon. What is the most likely result of this mutation in the protein product?

• A) a base-pair substitution
• B) a nucleotide mismatch
• C) a frameshift mutation
• D) a polypeptide missing an amino acid
• E) a nonsense mutation

---

Definitions:

Systematic

Methodical and organized in approach, often used to describe procedures that follow a fixed plan or system.

Resilience

The capacity to recover quickly from difficulties; toughness.

Child Characteristics

Attributes, traits, or behaviors that are typical or identifying of children at various stages of development.

Cross-Sectional

Involving or relating to analysis, study, or observation of subjects from various segments or groups at a single point in time.