Which Observation Suggested to Sutherland (1971 Nobel Prize Winner) the Involvement

question 60

Multiple Choice

Which observation suggested to Sutherland (1971 Nobel Prize winner) the involvement of a second messenger in adrenaline's effect on liver cells?

• A) Receptor studies indicated that adrenaline was a ligand.
• B) Glycogen breakdown was observed only when adrenaline was administered to intact cells.
• C) Glycogen breakdown was observed when adrenaline and glycogen phosphorylase were combined in a cell-free system.
• D) Adrenaline was known to have different effects on many types of cells.

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