Which Observation Suggested to Sutherland the Involvement of a Second

question 5

Multiple Choice

Which observation suggested to Sutherland the involvement of a second messenger in adrenalineadrenaline's effect on liver cells?

• A) Enzymatic activity was proportional to the amount of calcium added to a cell-free extract.
• B) Receptor studies indicated that adrenaline adrenalinewas a ligand.
• C) Glycogen breakdown was observed only when adrenaline adrenalinewas administered to intact cells.
• D) Glycogen breakdown was observed only when adrenaline adrenalineand glycogen phosphorylase were mixed.

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Definitions:

Direct Labor-Hours

The total hours worked directly on the production or manufacturing of goods, often used to allocate manufacturing overhead.

Denominator Activity

The level of activity used to compute the predetermined overhead rate.

Applied Factory Overhead

The portion of factory overhead costs assigned to each unit of production, based on an estimated or predetermined rate.

Electrical Motor

A device that converts electrical energy into mechanical energy, commonly used in appliances, industrial equipment, and vehicles.