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Characterisation of the Complete Three-Dimensional Structure of a Newly Purified

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Characterisation of the complete three-dimensional structure of a newly purified protein suggests that it catalyses the breakdown of a large substrate. The protein consists of a single polypeptide chain. It has a large pocket that appears to be the binding site for the substrate and a smaller indentation that appears to be the binding site for a regulatory molecule. What do these structural observations suggest about the mechanism by which the activity of this protein is likely regulated?


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