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Use the following to answer questions
Scenario I
Scenario I is based on fabricated data inspired by the following study:
Pande, A. C., Crockatt, J. C., Feltner, D. E., et al. (2003) . Pregabalin in generalized anxiety disorder: a placebo-controlled trial. The American Journal of Psychiatry, 160(3) , 533-540.
Effect of Pregabalin on Anxiety
Pande and colleagues examined whether pregabalin (brand name Lyrica) was as effective as lorazepam (brand name Ativan) in treating anxiety. To that end, they administered either a low dose of pregabalin, a high dose of pregabalin, lorazepam, or placebo to participants for four weeks, then measured the participants' anxiety using the Hamilton Anxiety Rating Scale. The researchers found that not only did the high dose of pregabalin significantly reduce anxiety, but that it also reduced anxiety as well as lorazepam. The results of the study (Figure 1) indicate that pregabalin may be an effective alternative to lorazepam to treat anxiety in adults.
Figure 1. Hypothetical results of Pande et al (2003) showing the impact of each treatment on anxiety level. Anxiety was measured using the Hamilton Anxiety Rating Scale.
-(Scenario I) Which of the following is an ethical issue apparent in Figure 1?
Missed Menstrual Period
A condition where a woman does not experience her monthly menstrual bleeding at the expected time.
Central Obesity
A pattern of fat distribution characterized by excess fat around the midsection, which is associated with an increased risk of various health conditions.
Cushing's Syndrome
A hormonal disorder caused by prolonged exposure of the body's tissues to high levels of the hormone cortisol, leading to a variety of symptoms and health issues.
Moon-Shaped Face
A facial appearance characterized by rounding of the face, often associated with certain medical conditions or steroid use.
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