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A Comparison of 11,000 Protein-Coding Genes from Humans and Chimpanzees

question 35

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A comparison of 11,000 protein-coding genes from humans and chimpanzees revealed a significantly higher ratio of nonsynonymous to synonymous polymorphism in humans compared to the ratio of nonsynonymous to synonymous substitutions between the two species, that is, pN/pS > dN/dS. What does this indicate about the variation in human populations?


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