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The Rate of Mutation to a Recessive Lethal Allele Is

question 33

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The rate of mutation to a recessive lethal allele is 0.000001. What is the equilibrium frequency this allele? (Recall that the equilibrium frequency for a recessive allele under mutation-selection balance is q = s, where is the rate of mutation to the disease allele and s is the selection coefficient against that allele. In the case of a lethal allele, s 1.)


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