Phenylephrine (PE, See the Structure Below) Is a Nasal Decongestant

question 132

Multiple Choice

Phenylephrine (PE, see the structure below) is a nasal decongestant and is the active ingredient in Sudafed, which contains phenylephrine hydrochloride (PEHCl) . This conjugate acid of phenylephrine (PEH⁺) has a pK_a = 5.5. At a physiological pH of 7.4. what is the ratio of concentrations, [PE]/[PEH⁺]?

• A) 6.7
• B) 0.01
• C) 0.14
• D) 79
• E) 21

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