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Which of the following trends in nucleophilicity are correct?
I. Everything else being equal, a negatively charged nucleophile will react faster than a neutral one.
II. Generally, species containing elements of high electronegativity are good nucleophiles.
III. Anionic nucleophiles are more reactive in polar and aprotic solvents than in polar and protic solvents
IV. Generally, nucleophilicity is increasing with the increase in size of an atom.
V. Bulky groups adjacent to the nucleophilic atom enhance the nucleophilicity and reactivity of the species.
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