A Population of Cells Is Treated with a Polypeptide Hormone

question 4

Multiple Choice

A population of cells is treated with a polypeptide hormone that induces mitosis and the hormone's cell surface receptor is isolated after 15 minutes and subjected to fragmentation and mass spectrometry. Several of the peaks show a slight shift as compared to the same protein from cells not treated with the hormone. What is the most likely explanation of this phenomenon?

• A) Phosphorylation of some amino acid residues.
• B) mRNA editing resulting in a slightly different amino acid sequence.
• C) Alternative exon usage.
• D) Proteolytic processing.

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