In Shotgun Sequencing, How Is a Complete Sequence of a Genome

question 8

Multiple Choice

In shotgun sequencing, how is a complete sequence of a genome reconstructed?

• A) The entire genome is directly sequenced chromosome by chromosome.
• B) The genome is fragmented and sequences of each fragment are arranged so that overlapping regions are identified.
• C) The sequences of a large number of individuals is obtained and "averaged" to obtain the complete sequence.
• D) The position of each marker and gene are first mapped relative to regions for which the genomic sequence is not known.

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Definitions:

Cash Basis

An accounting method where revenue is recorded when cash is received, and expenses are recorded when cash is paid out, without regard to when the transactions actually occur.

Indirect Method

A technique used in cash flow statement preparation that adjusts net income for changes in non-cash accounts to compute net cash provided by operating activities.

Patent Amortization

The gradual expense recognition of a patent's cost over its useful life to reflect the consumption of the patent's value over time.

Net Income

Net income is the total profit of a company after all expenses, including taxes and operational costs, have been subtracted from total revenue.