The Difference Between the Polymerases Used in Translesion Synthesis Repair

question 26

Multiple Choice

The difference between the polymerases used in translesion synthesis repair and general DNA replication is

• A) the polymerase used in translesion synthesis has a pocket that can accommodate the lesions while DNA pol III's pocket cannot.
• B) there is no real difference between the polymerases except that the translesional polymerase is not part of the replication complex.
• C) the polymerase used in translesion synthesis has a pocket that cannot accommodate the lesions, that is part of the mechanism by which the lesions are removed.
• D) the polymerase used to remove the lesion has a modified nucleotide binding pocket allowing for mispairing of nucleotides.

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