Hemophilia a Is an X-Linked Blood Clotting Disorder

question 2

Multiple Choice

Hemophilia A is an X-linked blood clotting disorder. A normal man and a woman with hemophilia A have a child with Turner Syndrome. This child does not have hemophilia. In whom did non-disjunction occur? In meiosis I or meiosis II?

• A) Woman; meiosis I
• B) Woman; meiosis II
• C) Man; meiosis I
• D) Man; meiosis II
• E) Woman; there is not enough information to tell if the nondisjunction happened in meiosis I or II.

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Definitions:

Carboxylate Ion

A negatively charged ion (an anion) that results when a carboxylic acid loses a hydrogen ion from its carboxyl group.

Ether Solution

A solution in which an ether, a class of organic compounds containing an oxygen atom connected to two alkyl or aryl groups, serves as the solvent.

Aqueous NaOH

A solution of sodium hydroxide in water, commonly used as a strong base in chemical reactions and industrial processes.

pKa

A quantitative measure of the strength of an acid in solution, defined as the negative logarithm of its acid dissociation constant.