The Nuclear Genome of a Single Human Cell (I

question 3

Multiple Choice

The nuclear genome of a single human cell (i.e., the entire diploid complement) contains about 6.6 billion (6.6 × 10⁹) base pairs of DNA.If synthesis at each replication fork occurs at an average rate of 50 nucleotides per second, all the DNA is replicated in 5 minutes.Assume that replication is initiated simultaneously at all origins.How many origins of replication exist in a human diploid genome?

• A)220, 000
• B)440, 000
• C)880, 000
• D)2)64 × 10⁷
• E)1)32 × 10⁸

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