The Nuclear Genome of a Single Human Cell (I

question 11

Multiple Choice

The nuclear genome of a single human cell (i.e., the entire diploid complement) contains about 6.6 billion (6.6 × 10⁹) base pairs of DNA.If synthesis at each replication fork occurs at an average rate of 50 nucleotides per second, all the DNA is replicated in 5 minutes.Assume that replication is initiated simultaneously at all origins.Assuming that the origins are approximately equally distributed across the chromosomes, what is the average number of origins per human chromosome?

• A)4783
• B)19, 130
• C)4)6 × 10⁶
• D)1)21 × 10⁹
• E)2)9 × 10¹⁰

---

Definitions:

Preemption

The doctrine that allows a higher level of government to override or prevent actions of a lower level of government in certain areas.

French and Indian War

A conflict between 1754 and 1763 in North America, part of a global struggle between France and Britain, which ultimately led to British dominance in the continent.

Colonial Defense

Strategies and actions taken by a colony to protect itself from military threats and secure its interests during the colonial period.

British Government

The central government of the United Kingdom of Great Britain and Northern Ireland, which operates under a parliamentary system.