Explain the Effect on DNA Replication of Mutations That Destroy

question 9

Essay

Explain the effect on DNA replication of mutations that destroy each of the following activities in DNA polymerase. Also, for each kind of mutation, how might you detect the effect in an in vitro replication reaction?
a. 5'to 3' polymerase
b. 5'to 3' exonuclease
c. 3' to 5' exonuclease

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