How Is Colchicine Useful for Studying Chromosomal Mutations

question 19

Multiple Choice

How is colchicine useful for studying chromosomal mutations?

• A)Colchicine inhibits microtubule polymerization, which stalls cells in metaphase with condensed chromosomes that can be observed with a microscope.
• B)Colchicine induces chromosome condensation during interphase, which allows the visualization of interphase chromosomes.
• C)Colchicine causes chromosomal breakage, leading to inversions and translocations that can be observed with a microscope.
• D)Colchicine aids in the formation of microtubules during mitosis, which promotes anaphase and completion of the cell cycle.
• E)Colchicine is an inhibitor of oxidative phosphorylation.Reduced mitochondrial function slows down mitosis and increases the number of metaphase cells.

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