The Following Microarray Data Are Shown for Four Human Genes

question 36

Multiple Choice

The following microarray data are shown for four human genes.Two samples were hybridized to the microarray in this experiment.One sample was cDNA generated from mRNA of a tissue culture cell line that was originally derived from a B-cell leukemia.The other sample was cDNA generated from normal, mature neural tissue. - Vertical stripes mean hybridization to cancerous B-cell cDNA only.
- Horizontal stripes mean hybridization to normal neural cell cDNA only.
- Completely filled in means hybridization to both cDNA types.
- Blank means hybridization to neither cell's cDNA. The gene sequences contained in spot 2 are present only in the B-cell cancer sample.What is a possible function for this gene, based on the microarray data?

• A)This gene may be involved in neurotransmitter release at the synapse since B cells are known to be involved in cell-to-cell signaling.
• B)This gene may be involved in activating cell growth, so it is switched on in the cancer cell line that is growing rapidly.
• C)This gene is involved in the immune function of the B cell because that is the cell type from which this cancer line was initially derived.
• D)This gene may be involved in neurotransmitter release at the synapse since B cells are known to be involved in cell-to-cell signaling, and it may also be involved in activating cell growth, so it is switched on in the cancer cell line that is growing rapidly.
• E)This gene may be involved in activating cell growth, so it is switched on in the cancer cell line that is growing rapidly, and it is also involved in the immune function of the B cell because that is the cell type from which this cancer line was initially derived.

---

Definitions:

Production Costs

The costs incurred by a business in the process of manufacturing a product or providing a service, including raw materials, labor, and overhead expenses.

Product Life Cycle Costing

A method used to evaluate the total cost of ownership of a product across its entire life cycle from design through disposal, aiming to understand and manage costs better.

Responsibility Centres

Units or departments within an organization for which managers are responsible for controlling costs, generating revenue, or managing investments.

Design

This involves creating a plan or convention for the construction of an object, system, or measurable human interaction, taking into account aesthetic, functional, and many other considerations.