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You Identify an RFLP in Mice by Digesting Genomic DNA

question 40

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You identify an RFLP in mice by digesting genomic DNA with HindIII enzyme and radiolabeling a piece of probe DNA.Southern blot analysis shows that the probe detects a 2-kb fragment in one strain of mice and a 4-kb fragment in another strain of mice.The two mice strains are crossed to produce an F1 generation.Two F1 siblings are mated to produce a dozen F2 progeny.You isolate genomic DNA from several F1 and F2 individuals, digest with HindIII, and perform a Southern blot with the same probe. How many bands would be seen in the Southern blot of an F2 individual?

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