Aniridia Is a Human Condition in Which the Eye Has

question 55

Multiple Choice

Aniridia is a human condition in which the eye has no iris. The protein encoded by the gene responsible for aniridia is very nearly identical to the protein product of the fly Eyeless protein. What experiment could provide evidence that the two genes are functionally equivalent?

• A)Introduce the aniridia mutation into Drosophila embryos to look for iris formation.
• B)Sequence the Eyeless and aniridia DNA sequences and regulators.
• C)Use the Eyeless mRNA as a probe in other invertebrate and non-mammalian species.
• D)Introduce the mouse aniridia wild-type sequence into the fly egg to see whether mouse eyes develop.
• E)Introduce the mouse aniridia wild-type sequence into the fly egg to see whether fly eyes develop.

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Definitions:

Fertilization

Union of sperm and ovum to produce a zygote; also called conception.

Expulsion

The act of forcing out or ejecting something or someone from a place or situation.

Menstrual Cycle

The regular natural change that occurs in the female reproductive system that makes pregnancy possible, typically lasting about one month.

Fertile Window

The time in a woman's menstrual cycle during which she has the highest chance of becoming pregnant, typically a few days before and including the day of ovulation.