Suppose There Is (Hypothetical)evidence That a Gene in Mice Produces

question 11

Multiple Choice

Suppose there is (hypothetical) evidence that a gene in mice produces a substance that induces twitchiness in hind leg muscles. A female mouse of a true-breeding twitchy strain is mated with a male of a true-breeding non-twitchy strain. All progeny are twitchy. Which of these procedures would you use to provide evidence for your hypothesis that twitchiness is due to mtDNA?

• A)Sequence the mtDNA of the twitchy mother.
• B)Breed twitchy male progeny with normal females to show no paternal inheritance.
• C)Breed twitchy female with twitchy male F1 mice to verify there is maternal inheritance.
• D)Backcross twitchy female offspring with normal fathers.
• E)Sequence the mtDNA of the twitchy male offspring.

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