You Are a Genetic Counselor Working with a Phenotypically Normal

question 42

Multiple Choice

You are a genetic counselor working with a phenotypically normal young couple who have been referred because the wife has a family history of a mitochondrial disorder that results in considerable dysfunction. What is the most important consideration you can suggest?

• A)to refrain from having children that are hers biologically
• B)that she be tested to find out what percentage of her mitochondria bear the mutation
• C)that both husband and wife have mtDNA testing for the sequence in question
• D)that her affected mother's DNA be tested
• E)that they consider having only sons

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Definitions:

Neurotrophic Factor

Neurotrophic factors are a family of proteins that are responsible for the growth, survival, and maintenance of neurons during development and in the adult nervous system.

Brain-derived

Pertaining to substances or factors that originate from the brain, such as brain-derived neurotrophic factor (BDNF) which supports neuron growth and survival.

Neural Plasticity

The ability of the nervous system to change and adapt, both in structure and function, in response to experiences or injuries.

Neuropsychological Tests

Neuropsychological tests are assessments used to evaluate memory, problem-solving, attention, language, and other cognitive abilities, often to diagnose brain injuries or diseases.