Subtelomeres Are Blocks of Homologous DNA Sequences Close to the Ends

question 26

Multiple Choice

Subtelomeres are blocks of homologous DNA sequences close to the ends of chromosomes. In a worldwide population of humans, when sequences of chromosomes 4q and 10q subtelomeres were analyzed only 17 4q and 8 10q haplotypes were found among African, European, and Asian groups. Which of the following might be among the results or conclusions of this analysis?

• A)finding that few or no interchromosomal exchanges can occur among these chromosomes
• B)a conclusion that all haplotypes were present before the human population migrated from Africa
• C)reporting that haplotype polymorphism shows no response to natural selection
• D)finding greater than 80% variation between homologous ends of chromosomes in humans
• E)a conclusion that assigning chromosomal origin of repeat arrays by using specific restriction enzymes is possible only in a population with the same ethnic origin

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