In Mapping the HD Gene Associated with Huntington Disease, Eventually

question 20

Short Answer

In mapping the HD gene associated with Huntington disease, eventually researchers narrowed down their hunt to four candidate genes within the mapped region. How did they identify one of these as the definitive HD gene?

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Definitions:

Narcolepsy

A sleep disorder characterized by excessive daytime sleepiness and sudden attacks of sleep.

Infancy

The earliest stage in human development, extending from birth to approximately 2 years of age, marked by rapid physical and cognitive growth.

REM Sleep

A stage of sleep characterized by rapid eye movements, more dreaming, and bodily movement; considered important for emotional regulation and memory consolidation.

Mammals

Warm-blooded vertebrate animals characterized by the presence of mammary glands, which females use to feed their young.