In a Disease Associated with a Nucleotide Repeat, Anticipation Is

question 11

Multiple Choice

In a disease associated with a nucleotide repeat, anticipation is often noticed in subsequent generations, usually associated with a more severe phenotype. Which of the following is a more likely cause of anticipation?

• A)The CAG alleles with a high number of repeats are unstable and change size from generation to generation.
• B)Subtle phenotypic nuances are more often sought by a physician.
• C)Family members are exposed to the same mutagens.
• D)Highly repeated sequences are expressed more often.
• E)The sequences have greater stability in later generations.

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Definitions:

Frontal Lobes

Regions of the brain located at the front of each cerebral hemisphere, involved in decision making, problem solving, control of purposeful behaviors, consciousness, and emotions.

Occipital Lobes

The area of the cerebral cortex situated at the brain's rear, tasked with interpreting visual data.

Visual Cortex

The region of the brain responsible for processing visual information received from the eyes.

Auditory Cortex

The region of the brain that is responsible for processing auditory information, located in the temporal lobes.