Why Are COPD Patients with Chronic Hypercapnia Unable to Hyperventilate

question 33

Multiple Choice

Why are COPD patients with chronic hypercapnia unable to hyperventilate to decrease their PaCO₂?

• A) The central chemoreceptors respond only to O₂ concentration changes, not to changes in CO₂.
• B) The central chemoreceptors are insensitive to acute or chronic changes in PaCO₂.
• C) The central chemoreceptors respond to [H⁺], not the CO₂ molecule.
• D) The central chemoreceptors do not respond to changes in hydrogen ion concentration or PaCO₂.

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