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A Patient with Progressively Deteriorating Lower Extremity Motor and Sensory

question 8

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A patient with progressively deteriorating lower extremity motor and sensory function is having a lumbar puncture. What finding suggests that this patient has Guillain-Barré syndrome (GBS) ?


Definitions:

Gene Targeting

A genetic technique that uses homologous recombination to change an endogenous gene's sequence to study gene function or create specific animal models for human disease.

Knock-Out Gene

A gene that has been deliberately inactivated or deleted through genetic engineering to study its function by observing the resulting phenotype.

Orthologous Genes

Homologous genes found in different species because they were inherited from a common ancestor.

Antibiotic Medium

A growth medium infused with antibiotics used in laboratory settings to select for or against microorganisms sensitive to the specific antibiotics.

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