A Transition-State Analog

question 84

Multiple Choice

A transition-state analog:

• A) is less stable when binding to an enzyme than the normal substrate.
• B) resembles the active site of general acid-base enzymes.
• C) resembles the transition-state structure of the normal enzyme-substrate complex.
• D) stabilizes the transition state for the normal enzyme-substrate complex.
• E) typically reacts more rapidly with an enzyme than the normal substrate.

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Definitions:

Feedback Inhibition

A process where the end product of a metabolic pathway acts as an inhibitor of an enzyme within that pathway, regulating its own production.

Posttranslational Control

Regulation of gene expression that controls activity or functions of proteins, usually by phosphorylation or other chemical modifications of the protein. Compare with transcriptional-level control, translational-level control, and posttranscriptional control.

Translational Control

The regulation of protein synthesis in a cell by various mechanisms that act on the process of translating RNA into protein.

Transcriptional Control

The regulation of gene expression at the transcription stage, determining when and how much RNA is produced from a gene.