You Are Examining the Effects of a Mutation in the Proximal

question 33

Multiple Choice

You are examining the effects of a mutation in the proximal histidine of a heme-containing protein. This mutation has changed the histidine into an alanine. Based on your knowledge of the role of heme in hemoglobin and how it is coordinated in the protein, what is the MOST likely effect of the mutation?

• A) Heme will no longer be bound in the protein.
• B) The iron in heme will be fully coordinated.
• C) The iron in heme will have two uncoordinated bonds.
• D) The heme will be able to bind to O₂ more effectively than it will to CO.
• E) There will be no effect on the protein due to this mutation.

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Definitions:

Ethnic Group

A community or population made up of people who share a common cultural background, heritage, language, or religion, which distinguishes them from other groups.

Shared Language

A language or form of communication mutually understood and used by members of a specific group or community.

Customs

Traditional practices, beliefs, or behaviors that are characteristic of a particular community, society, or culture.

Ted Kaczynski

An American domestic terrorist, also known as the Unabomber, who engaged in a nationwide bombing campaign against people involved with modern technology, motivated by his belief in the negative effects of industrial-technological society.