Which Statement Does NOT Describe a Reason Why the Major

question 68

Multiple Choice

Which statement does NOT describe a reason why the major groove is more suited for sequence specificity interactions by DNA binding proteins?

• A) The methyl group of T residues is found in the major groove.
• B) The major groove is larger, allowing more space for protein side chains.
• C) The minor groove is negatively charged because of the crowding by phosphates.
• D) Hydrogen bond donor and acceptor patterns are different in the major groove for different base pairs.
• E) Two hydrogen bond acceptors exist for all base pairs in the minor groove.

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