An Example of Coordinate Control Is the Down-Regulation of Ribosomal

question 60

Multiple Choice

An example of coordinate control is the down-regulation of ribosomal RNA synthesis in response to amino acid starvation, which will cause synthesis of ribosomal proteins to be limited. What is the CORRECT order of the following events that participate in the signaling process?
1. Binding of stringent factor to the ribosome
2. Formation of the unusual nucleotide ppGpp
3. Formation of the unusual nucleotide pppGpp 4. Binding of uncharged tRNA in the ribosomal A-site

• A) 1, 4, 2, 3
• B) 1, 4, 3, 2
• C) 4, 1, 2, 3
• D) 4, 1, 3, 2
• E) 4, 2, 1, 3

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