Retroviral Genomes Tend to Mutate at a Very High Rate

question 48

Multiple Choice

Retroviral genomes tend to mutate at a very high rate. What statement BEST explains this observation?

• A) The RNA genome is highly susceptible to chemical damage.
• B) Specific enzymes in cells will modify the genome as a protection against infection.
• C) RNA phosphodiester bonds will tend to hydrolyze spontaneously.
• D) The virus changes the sequence to prevent antibody binding to the viral genome.
• E) Reverse transcriptase lacks a 3' to 5'exonuclease activity.

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