A Plasmid Containing 16,700 Base Pairs Has a Superhelical Density

question 52

Short Answer

A plasmid containing 16,700 base pairs has a superhelical density of -0.015 (superhelical density = writhe/twist). Assuming the duplex is all B-DNA, calculate the number of rounds of a Type II topoisomerase that would be required to relax this DNA (as close as possible to completely relaxed).

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Latin

An ancient language of Rome and its empire, widely used historically as a language of scholarship and administration.

Crab

A crustacean with a broad carapace, stalked eyes, and five pairs of legs, the first pair being modified as pincers.

Bronchogenic Carcinoma

A type of lung cancer arising from the bronchial epithelium, the tissue lining the airways of the lungs.

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