Ibuprofen Is a Weak Acid with a PK_a of 4

question 15

Multiple Choice

Ibuprofen is a weak acid with a pK_a of 4.9 (shown with the ionizable hydrogen with a star) . It is absorbed through the stomach and the small intestine as a function of polarity-charged and very polar molecules are absorbed slowly; neutral hydrophobic molecules absorb quickly. If the stomach pH is about 1.5 and the small intestine pH is about 6, where (and why) will more ibuprofen be absorbed into the bloodstream?

• A) More ibuprofen will be absorbed in the small intestine because it will be uncharged due to the pH being greater than the pK_a^.
• B) More ibuprofen will be absorbed in the stomach because it will be uncharged due to the pH being lower than the pK_a.
• C) More ibuprofen will be absorbed in the small intestine because it will be charged due to the pH being greater than the pK_a.
• D) More ibuprofen will be absorbed in the stomach because it will be charged due to the pH being lower than the pK_a.
• E) Ibuprofen will be absorbed equally well in both the stomach and small intestine.

Describe structural and functional adaptations in the circulatory systems of vertebrates in response to environmental conditions.

Comprehend the mechanics and significance of blood pressure and its regulation.

Recognize and understand the role of pacemaker cells and the conduction system in the heart.

Understand the physiological differences between the circulatory systems of mammals, fish, reptiles, and other vertebrates.

---

Definitions:

Seeking Recognition

The act of pursuing acknowledgment or validation from others for one's achievements or qualities.

Norms

Established standards of behavior or expectations within a group or society.

Team Effectiveness

The degree to which a team is able to achieve its goals, objectives, and missions successfully through coordinated efforts and collaboration among its members.

Workforce Diversity

Refers to a workplace that includes individuals of varying gender, age, religion, race, ethnicity, cultural background, sexual orientation, languages, education, and abilities.