The E3 Subunit of Pyruvate Dehydrogenase $\alpha$ -Ketoglutarate Dehydrogenase and the Branched-Chain

question 60

Essay

The E3 subunit of pyruvate dehydrogenase, $\alpha$ -ketoglutarate dehydrogenase and the branched-chain $\alpha$ -keto acid dehydrogenase complex is identical in each multi-enzyme complex. What reaction is catalyzed by this subunit, and why it does it make sense that it is common while E1 and E2 are not?

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