Which Statement Is FALSE Regarding Regulation of the Pyruvate Dehydrogenase

question 81

Multiple Choice

Which statement is FALSE regarding regulation of the pyruvate dehydrogenase complex?

• A) In E. coli, a high ratio of [NAD⁺]/[NADH] activates the complex.
• B) In E. coli, high levels of ATP enhance the activity of pyruvate dehydrogenase kinase.
• C) In plants, NH₄⁺ inhibits the complex by enhancing the activity of pyruvate dehydrogenase kinase.
• D) In mammals, both fatty acids and acetyl-CoA inhibit the complex.
• E) In skeletal muscle, both NAD⁺ and Ca₂⁺ activate the complex.

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