Arsenic Inhibits the Pyruvate Dehydrogenase Complex by Inactivating the Dihydrolipoamide $\alpha$

question 93

Multiple Choice

Arsenic inhibits the pyruvate dehydrogenase complex by inactivating the dihydrolipoamide component of dihydrolipoyl transacetylase. Which enzyme is also MOST likely to be inhibited by arsenic?

• A) GAP dehydrogenase
• B) isocitrate dehydrogenase
• C) succinyl-CoA synthetase
• D) malate dehydrogenase
• E) \(\alpha\)-ketoglutarate dehydrogenase

---

Definitions:

National Amendment

A change or addition to the Constitution of a nation, often requiring a specific process for ratification.

Constitutional Amendments

Changes or additions to the U.S. Constitution, proposed to adjust governance according to evolving societal values and needs, requiring ratification by a significant majority.

Oregon System

A set of political reforms in the early 20th century in Oregon, including the initiative, referendum, and recall, aimed at increasing public participation in government.

Direct Primary

A preliminary election in which members of a party nominate candidates for office, giving the power of selecting candidates directly to the voters.