There Is Reciprocal Regulation of Glycolytic and Gluconeogenic Reactions Interconverting

question 29

Multiple Choice

There is reciprocal regulation of glycolytic and gluconeogenic reactions interconverting fructose-6-phosphate and fructose-1,6-bisphosphate. Which statement about this regulation is NOT correct?

• A) Fructose-2,6-bisphosphate activates phosphofructokinase-1.
• B) Fructose-2,6-bisphosphate inhibits fructose-1,6-bisphosphatase.
• C) The fructose-1,6-bisphosphatase reaction is exergonic.
• D) The phosphofructokinase-1 reaction is endergonic.
• E) This regulation allows control of the direction of net metabolite flow through the pathway.

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