Which Statement Accurately Describes the Effect of Insulin on the Expression

question 25

Multiple Choice

Which statement accurately describes the effect of insulin on the expression of the gene for glucose 6-phosphatase?

• A) Insulin triggers the phosphorylation of PKB, which then phosphorylates FOXO-1. Phosphorylation of FOXO-1 causes a decrease in its degradation by the proteasome, which is associated with an increase in the expression of the gene for glucose 6-phosphatase.
• B) Insulin activates PKB by phosphorylation, which then phosphorylates FOXO-1. Phosphorylation of FOXO-1 causes an increase in its degradation by the proteasome, which is associated with an increase in the expression of the gene for glucose 6-phosphatase.
• C) Insulin leads to the activation of PKA, which then phosphorylates FOXO-1. Phosphorylation of FOXO-1 causing a decrease in its degradation by the proteasome, which is associated with a decrease in the expression of the gene for glucose 6-phosphatase.
• D) Insulin leads to the activation of PKB, which then phosphorylates FOXO-1. Phosphorylation of FOXO-1 causing an increase in its degradation by the proteasome, which is associated with a decrease in the expression of the gene for glucose 6-phosphatase.
• E) Insulin activates phosphoprotein phosphatase, which then dephosphorylates FOXO-1. Dephosphorylation of FOXO-1 causes a decrease in its degradation by the proteasome and an increase in the expression of the gene for glucose 6-phosphatase.

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Definitions:

Foreseen Danger

A risk or hazard that was known or could have been anticipated prior to an event.

Poisonous Snake

A snake species that has venom which is harmful or fatal to humans and other animals upon biting.

Confinement

The state of being restricted or limited within certain boundaries.

Serious Injury

An injury that poses a significant threat to an individual's health or life, often requiring medical intervention.