Which Statement Is NOT True for G Protein-Coupled Receptors (GPCRs)

question 37

Multiple Choice

Which statement is NOT true for G protein-coupled receptors (GPCRs) ?

• A) Agonists mimic the effect of the natural ligand.
• B) Antagonists block the normal effect of the natural ligand.
• C) GPCRs interact with heterodimeric G proteins.
• D) GPCRs are have seven transmembrane helices.
• E) There exist >100 orphan GPCRs in the human genome with no known ligand.

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