Reagents a and B Both React Covalently with Primary Amino

question 44

Essay

Reagents A and B both react covalently with primary amino groups such as those of phosphatidylethanolamine. Reagent A permeates erythrocytes, but reagent B is impermeant. Both A and B are available in radioisotopically labeled form. Describe a simple experiment by which you might determine whether the phosphatidylethanolamine of erythrocyte membranes is located in the outside face of the lipid bilayer, the inside face, or in both.

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Definitions:

Estimable

Capable of being estimated or approximated in quantity or degree.

Remote Event

An event or condition with a very low chance of occurring, often considered insignificant in financial forecasting and analysis.

Probable Likelihood

This term refers to the high chance of occurrence or expectation that a specific event or outcome will happen.

Liability

Financial obligations or debts that a company or individual owes to others, required to be settled over time.