A Newly Discovered Signaling Molecule That Binds to a G

question 51

Multiple Choice

A newly discovered signaling molecule that binds to a G protein-coupled receptor is being studied by using cells maintained in cell culture. Preliminary results show that the binding of this new ligand causes the activation of adenylyl cyclase. In the next part of this study, a non-hydrolyzable version of GTP (a form of GTP that cannot be converted to GDP) is added to the cell culture dishes and is taken up by the cells. Which of the following would you expect to observe?

• A)increased cAMP, decreased protein kinase A activity
• B)decreased cAMP, decreased protein kinase A activity
• C)decreased cAMP, increased protein kinase A activity
• D)increased cAMP, increased protein kinase A activity

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