The Signal Recognition Particle and Its Receptor on the Surface

question 112

Essay

The signal recognition particle and its receptor on the surface of the endoplasmic reticulum ensure that proteins destined for incorporation into cellular membranes or for export from the cell are translated into the endoplasmic reticulum so that they may be processed through the endomembrane system. If a mutation rendered the signal recognition particle receptor nonfunctional such that the receptor was no longer able to dissociate from the SRP, what would be the most obvious effect on the cell?

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