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You Are Investigating an Abnormal Eukaryotic Cell Line That Makes

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Essay

You are investigating an abnormal eukaryotic cell line that makes all of its mRNAs much longer than the mRNAs from normal cells. Intrigued, you examine the proteins in these abnormal cells and note that many of them are either much longer or much shorter than the normal proteins from nonmutant cells. Assuming there is just one mutant defect in these cells, which of the below possibilities is MOST likely?
A)A stop codon is mutated.
B)RNA polymerase does not recognize the terminator sequence.
C)The release factor is defective.
D)The spliceosome is nonfunctional.
E)The enzyme that adds the poly-A tail is defective.


Definitions:

Stimulus Generalization

The process by which a conditioned response is triggered by stimuli that are similar but not identical to the original conditioned stimulus.

Systematic Desensitization

A behavioral therapy technique used to reduce phobic responses and anxiety by gradually exposing the individual to the feared object or situation in a controlled way.

Counterconditioning

A behavior therapy technique that involves pairing a positive stimulus with a fear-evoking stimulus to reduce the fearful response.

Second-order Conditioning

A form of conditioning in which a stimulus is paired with a previously conditioned stimulus, leading to learning without the original unconditioned stimulus.

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