In Order to Test the Effects of a New Drug

question 174

Essay

In order to test the effects of a new drug, you isolate the messenger RNA molecules from both treated and untreated eukaryotic cells and separate them according to size using gel electrophoresis. In each lane of the gel, the shorter RNA molecules migrate more quickly through the gel and end up near the bottom of the gel while the longer RNAs migrate more slowly and remain near the top. The samples that were loaded into each of the four lanes are as follows:
Lane 1: the primary RNA transcripts isolated from the nucleus of untreated cells
Lane 2: the primary RNA transcripts isolated from the nucleus of cells treated with the drug being tested
Lane 3: RNA isolated from the cytosol of untreated cells
Lane 4: RNA isolated from the cytosol of cells treated with the drug being tested
Based on the information provided by the gel shown above, what cellular process appears to be affected by the new drug?

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Definitions:

Performance Review

A formal assessment in which the work performance of an employee is documented and evaluated.

Supportive

Providing assistance, encouragement, or emotional help to others in a way that promotes a positive environment or outcome.

Corrective

Designed to correct or rectify an error, fault, or undesirable outcome, often through specific interventions or adjustments.

Feedback

Information provided about reactions to a product, a person's performance of a task, etc., used as a basis for improvement.