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Two related but distinct neurological disorders are Prader-Willi syndrome (PWS) and Angelman syndrome (AS) . Children with PWS are obese, have weak muscle tone, and delayed development. Children with AS have severe speech impairment, developmental delay, intellectual disability, and problems with movement and balance. However, both disorders are due to the deletion of the same part of chromosome 15. When the deletion is in the copy of chromosome 15 that came from the father, the child has PWS, but when the deletion is in the copy of chromosome 15 that came from the mother, the child has AS. What hypothesis can explain these observations?
Grievous Losses
Refers to severe and deep losses that cause profound sorrow and distress.
Child
A young human being, usually under the age of puberty.
Grief Period
The duration of time during which an individual experiences intense sorrow and a range of emotional responses following the death of a loved one.
Adolescents
Individuals in the transitional stage of development between childhood and adulthood, typically characterized by significant physical, psychological, and social changes.
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